bpc157/legit FDA · CAT 2 · WADA · S0
Primary Sources the record

Full Citation Index

Every source cited on this site. All peer-reviewed, primary-record, or regulatory official documents. Linked to PubMed, PMC, and journal DOI pages.

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FIG. 01 · REFERENCE GRID

18 primary sources cited across this site — all indexed peer-reviewed publications, systematic reviews, or regulatory documents.

How This List Is Organized

References are numbered sequentially as they appear across the site. Each entry includes: authors, title, journal, year, DOI, and PubMed ID (PMID) or PMC ID where available. Outbound links point to PubMed (pubmed.ncbi.nlm.nih.gov), PubMed Central (pmc.ncbi.nlm.nih.gov), and journal DOI resolver pages. All references are to peer-reviewed publications, systematic reviews, narrative reviews, or official regulatory documents. No secondary or tertiary sources are cited.

Citations

  1. Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P. Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation. Journal of Orthopaedic Research. 2006;24(5):982–989.
    DOI: 10.1002/jor.20096 PMID: 16583442
  2. Chang CH, Tsai WC, Hsu YH, Pang JH. Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts. Molecules. 2014;19(11):19066–19077.
    DOI: 10.3390/molecules191119066 PMID: 25415472 PMC: PMC6271067
  3. Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S. Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing. Journal of Physiology and Pharmacology. 2009;60 Suppl 7:191–196.
    PMID: 20388964
  4. Cerovecki T, et al. Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat. Journal of Orthopaedic Research. 2010;28(9):1155–1161.
    DOI: 10.1002/jor.21107 Full text ↗
  5. Xue XC, Wu YJ, Gao MT, Li WG, Zhao N, Wang ZL, Bao CJ, Yan Z, Zhang YQ. Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats. World Journal of Gastroenterology. 2004;10(7):1032–1036.
    DOI: 10.3748/wjg.v10.i7.1032 PMID: 15052688
  6. Klicek R, Sever M, Radic B, Drmic D, Kocman I, Zoricic I, Vuksic T, Ivica M, Barisic I, Ilic S, et al. Pentadecapeptide BPC 157, in clinical trials as a therapy for inflammatory bowel disease (PL14736), is effective in the healing of colocutaneous fistulas in rats: role of the nitric oxide-system. Journal of Pharmacological Sciences. 2008;108(1):7–17.
    DOI: 10.1254/jphs.fp0072161 PMID: 18818478
  7. Vukusic D, Zenko Sever A, Sever M, Drmic D, Milavic M, Sikiric S, et al. Duodenocolic fistula healing by pentadecapeptide BPC 157 in rats. A cytoprotection viewpoint. Journal of Physiology and Pharmacology. 2024;75(1).
    DOI: 10.26402/jpp.2024.1.09 PMID: 38583442
  8. Sikiric P, Seiwerth S, Brcic L, Blagaic AB, Zoricic I, Sever M, et al. Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia). Full and distended stomach, and vascular response. Inflammopharmacology. 2006;14(5–6):214–221.
    DOI: 10.1007/s10787-006-1531-7 PMID: 17186181
  9. Sikiric P, Seiwerth S, Rucman R, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Current Neuropharmacology. 2016;14(8):857–865.
    DOI: 10.2174/1570159x13666160502153022 PMID: 27138887
  10. Perovic D, Kolenc D, Bilic V, Somun N, Drmic D, Elabjer E, Buljat G, Seiwerth S, Sikiric P. Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats. Journal of Orthopaedic Surgery and Research. 2019;14(1):199.
    DOI: 10.1186/s13018-019-1242-6 PMID: 31266512 PMC: PMC6604284
  11. Vukojevic J, Milavic M, Perovic D, Ilic S, Cilic AZ, Djuran N, Strbe S, Zoricic Z, Filipcic I, Brecic P, Seiwerth S, Sikiric P. Pentadecapeptide BPC 157 and the central nervous system. Neural Regeneration Research. 2022;17(3):482–487.
    DOI: 10.4103/1673-5374.320969 PMID: 34380875
  12. Jung YH, Kim H, Kim H, Kim E, Baik J, Kang H. The anti-nociceptive effect of BPC-157 on the incisional pain model in rats. Journal of Dental Anesthesia and Pain Medicine. 2022;22(2):97–107.
    DOI: 10.17245/jdapm.2022.22.2.97 PMID: 35449779
  13. He L, Feng D, Guo H, Zhou Y, et al. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs. Frontiers in Pharmacology. 2022;13:1026182.
    DOI: 10.3389/fphar.2022.1026182 PMID: 36588717 PMC: PMC9794587
  14. Japjec M, Horvat Pavlov K, Petrovic A, et al. Stable Gastric Pentadecapeptide BPC 157 as a Therapy for the Disable Myotendinous Junctions in Rats. Biomedicines. 2021;9(11):1547.
    DOI: 10.3390/biomedicines9111547 PMID: 34829776
  15. McGuire FP, Martinez R, Lenz A, Skinner L, Cushman DM. Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing. Current Reviews in Musculoskeletal Medicine. 2025;18(1).
    DOI: 10.1007/s12178-025-09990-7 PMID: 40789979 PMC: PMC12446177
  16. Yuan C, Demers A, Silva-Ortiz V, Hasoon JJ, Lee W, Dave K, Amirdelfan K, Burke HW, Christo PJ, Robinson CL. From Regeneration to Analgesia: The Role of BPC-157 in Tissue Repair and Pain Management. International Journal of Molecular Sciences. 2026;27(6):2876.
    DOI: 10.3390/ijms27062876 PMID: 41898733
  17. Concerning BPC-157, a natural pentadecapeptide, that acts as a cytoprotectant and is believed to protect the gastro-intestinal tract (GIT). Inflammopharmacology. 2025.
    DOI: 10.1007/s10787-025-01882-z PMID: 40759852
  18. Stable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats. Pharmaceutics. 2025;17(1):119.
    DOI: 10.3390/pharmaceutics17010119 PMID: 39861766