# BPC-157 Research References — Full Citation List > Complete citation list for the BPC-157 research literature referenced on this site: PubMed, PMC, journal DOIs, and regulatory documents. All sources are peer-reviewed or primary regulatory records. ## How This List Is Organized References are numbered sequentially as they appear across the site. Each entry includes: authors, title, journal, year, DOI, and PubMed ID (PMID) or PMC ID where available. All references are to peer-reviewed publications, systematic reviews, narrative reviews, or official regulatory documents. No secondary or tertiary sources are cited. ## Citations [1] Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P. Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation. Journal of Orthopaedic Research. 2006;24(5):982–989. DOI: 10.1002/jor.20096. PMID: 16583442. https://pubmed.ncbi.nlm.nih.gov/16583442/ [2] Chang CH, Tsai WC, Hsu YH, Pang JH. Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts. Molecules. 2014;19(11):19066–19077. DOI: 10.3390/molecules191119066. PMID: 25415472. PMC: PMC6271067. https://pmc.ncbi.nlm.nih.gov/articles/PMC6271067/ [3] Brcic L, Brcic I, Staresinic M, Novinscak T, Sikiric P, Seiwerth S. Modulatory effect of gastric pentadecapeptide BPC 157 on angiogenesis in muscle and tendon healing. Journal of Physiology and Pharmacology. 2009;60 Suppl 7:191–196. PMID: 20388964. https://pubmed.ncbi.nlm.nih.gov/20388964/ [4] Cerovecki T, et al. Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat. Journal of Orthopaedic Research. 2010;28(9):1155–1161. DOI: 10.1002/jor.21107. https://onlinelibrary.wiley.com/doi/abs/10.1002/jor.21107 [5] Xue XC, Wu YJ, Gao MT, Li WG, Zhao N, Wang ZL, Bao CJ, Yan Z, Zhang YQ. Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats. World Journal of Gastroenterology. 2004;10(7):1032–1036. DOI: 10.3748/wjg.v10.i7.1032. PMID: 15052688. https://pubmed.ncbi.nlm.nih.gov/15052688/ [6] Klicek R, Sever M, Radic B, Drmic D, Kocman I, Zoricic I, Vuksic T, Ivica M, Barisic I, Ilic S, et al. Pentadecapeptide BPC 157, in clinical trials as a therapy for inflammatory bowel disease (PL14736), is effective in the healing of colocutaneous fistulas in rats: role of the nitric oxide-system. Journal of Pharmacological Sciences. 2008;108(1):7–17. DOI: 10.1254/jphs.fp0072161. PMID: 18818478. https://pubmed.ncbi.nlm.nih.gov/18818478/ [7] Vukusic D, Zenko Sever A, Sever M, Drmic D, Milavic M, Sikiric S, et al. Duodenocolic fistula healing by pentadecapeptide BPC 157 in rats. A cytoprotection viewpoint. Journal of Physiology and Pharmacology. 2024;75(1). DOI: 10.26402/jpp.2024.1.09. PMID: 38583442. https://pubmed.ncbi.nlm.nih.gov/38583442/ [8] Sikiric P, Seiwerth S, Brcic L, Blagaic AB, Zoricic I, Sever M, et al. Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia). Full and distended stomach, and vascular response. Inflammopharmacology. 2006;14(5–6):214–221. DOI: 10.1007/s10787-006-1531-7. PMID: 17186181. https://pubmed.ncbi.nlm.nih.gov/17186181/ [9] Sikiric P, Seiwerth S, Rucman R, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Current Neuropharmacology. 2016;14(8):857–865. DOI: 10.2174/1570159x13666160502153022. PMID: 27138887. https://pubmed.ncbi.nlm.nih.gov/27138887/ [10] Perovic D, Kolenc D, Bilic V, Somun N, Drmic D, Elabjer E, Buljat G, Seiwerth S, Sikiric P. Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats. Journal of Orthopaedic Surgery and Research. 2019;14(1):199. DOI: 10.1186/s13018-019-1242-6. PMID: 31266512. PMC: PMC6604284. https://pmc.ncbi.nlm.nih.gov/articles/PMC6604284/ [11] Vukojevic J, Milavic M, Perovic D, Ilic S, Cilic AZ, Djuran N, Strbe S, Zoricic Z, Filipcic I, Brecic P, Seiwerth S, Sikiric P. Pentadecapeptide BPC 157 and the central nervous system. Neural Regeneration Research. 2022;17(3):482–487. DOI: 10.4103/1673-5374.320969. PMID: 34380875. https://pubmed.ncbi.nlm.nih.gov/34380875/ [12] Jung YH, Kim H, Kim H, Kim E, Baik J, Kang H. The anti-nociceptive effect of BPC-157 on the incisional pain model in rats. Journal of Dental Anesthesia and Pain Medicine. 2022;22(2):97–107. DOI: 10.17245/jdapm.2022.22.2.97. PMID: 35449779. https://jdapm.org/DOIx.php?id=10.17245/jdapm.2022.22.2.97 [13] He L, Feng D, Guo H, Zhou Y, et al. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs. Frontiers in Pharmacology. 2022;13:1026182. DOI: 10.3389/fphar.2022.1026182. PMID: 36588717. PMC: PMC9794587. https://pmc.ncbi.nlm.nih.gov/articles/PMC9794587/ [14] Japjec M, Horvat Pavlov K, Petrovic A, et al. Stable Gastric Pentadecapeptide BPC 157 as a Therapy for the Disable Myotendinous Junctions in Rats. Biomedicines. 2021;9(11):1547. DOI: 10.3390/biomedicines9111547. PMID: 34829776. https://pubmed.ncbi.nlm.nih.gov/34829776/ [15] McGuire FP, Martinez R, Lenz A, Skinner L, Cushman DM. Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing. Current Reviews in Musculoskeletal Medicine. 2025;18(1). DOI: 10.1007/s12178-025-09990-7. PMID: 40789979. PMC: PMC12446177. https://pmc.ncbi.nlm.nih.gov/articles/PMC12446177/ [16] Yuan C, Demers A, Silva-Ortiz V, Hasoon JJ, Lee W, Dave K, Amirdelfan K, Burke HW, Christo PJ, Robinson CL. From Regeneration to Analgesia: The Role of BPC-157 in Tissue Repair and Pain Management. International Journal of Molecular Sciences. 2026;27(6):2876. DOI: 10.3390/ijms27062876. PMID: 41898733. https://pubmed.ncbi.nlm.nih.gov/41898733/ [17] Concerning BPC-157, a natural pentadecapeptide, that acts as a cytoprotectant and is believed to protect the gastro-intestinal tract (GIT). Inflammopharmacology. 2025. DOI: 10.1007/s10787-025-01882-z. PMID: 40759852. https://pubmed.ncbi.nlm.nih.gov/40759852/ [18] Stable Gastric Pentadecapeptide BPC 157 as Therapy After Surgical Detachment of the Quadriceps Muscle from Its Attachments for Muscle-to-Bone Reattachment in Rats. Pharmaceutics. 2025;17(1):119. DOI: 10.3390/pharmaceutics17010119. PMID: 39861766. https://pubmed.ncbi.nlm.nih.gov/39861766/ --- For research purposes only. Not for human consumption. This site does not sell any product and is not affiliated with any vendor.